Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Salicylic Acid | HCID 338 | — |
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Salicyloyl chloride | HCID 74041 | — |
Reaction Steps
2-Hydroxy benzoic acid (1 g, 7.2 mmol) is dissolved in DCM (14 mL). To this mixture, thionyl chloride (1.57 mL, 22 mmol) and a catalytic amount of dry DMF are added. The resulting mixture is heated to 60° C. overnight, after which the resulting mixture is evaporated to give the desired product that is used as such.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09382254B2 |
|---|
| Source dataset | uspto-grants-2016_07 |
|---|
| ORD ID | ord-3081c8a37453493a897f71744ea54e17 |
|---|
| Source note | uspto-grants-2016_07 |
|---|
