HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodoethane → 6-(3-fluorophenyl)-N-ethylpyrido[3,2-d]pyrimidin-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodoethane | HCID 6340 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 6-(3-Fluorophenyl)pyrido[3,2-d]pyrimidin-4-amine | HCID 86703914 | — |
| Product | 6-(3-fluorophenyl)-N-ethylpyrido[3,2-d]pyrimidin-4-amine | HCID 86703917 | — |
Reaction Steps
Following the same reaction and purification procedure, the amine 1 (150 mg, 0.62 mmol) was treated with sodium hydride 60% dispersion in mineral oil (37 mg, 0.94 mmol) and iodoethane (0.05 mL, 0.62 mmol) to provide 6-(3-fluorophenyl)-N-ethylpyrido[3,2-d]pyrimidin-4-amine 29.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09382241B2 |
| Source dataset | uspto-grants-2016_07 |
| ORD ID | ord-2f9ffb597818486abf5d6e2f6fe41d32 |
| Source note | uspto-grants-2016_07 |