Dichloroacetyl chloride → HCID 118519597, compound

Participants

Reaction Steps

Using compound (3S,3 aS)-3-aminomethyl-7-(3-oxomorpholin-4-yl)-3a,4-dihydrobenzo[b]oxazolo[3,4-d][1,4]oxazin-1 (3H)-one (the product of step (e) in Example 1) (40 mg, 0.178 mmol) and 2,2-dichloro acetyl chloride (27.6 mg, 0.188 mmol) as starting materials, preparation following the method as described in Example 1(f) afforded white solid 20 mg, yield: 37%.

Provenance & Evidence