HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → HCID 15819152, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | HCID 21723398 | HCID 21723398 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 15819152 | HCID 15819152 | — |
Reaction Steps
2.0 g 16α-azido-3-methoxy-estra-1,3,5(10)-triene-17α-ol are reduced with 40 ml methanol, 4 ml of 80% hydrazine hydrate and 2 spatula tips Raney nickel in the above described manner. Recrystallization is performed from methanol/ether. Yield: 1.3 g (71%), F: at 145° C. conversion, at 193-198° C. melting; [α]D+44° (pyridine);
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09382288B2 |
| Source dataset | uspto-grants-2016_07 |
| ORD ID | ord-8d9bfac14cdd4b1aa0b1170768915492 |
| Source note | uspto-grants-2016_07 |