Sodium Azide → HCID 86698318, compound

HRID 1050292Notes

Reaction equation

HRID 1050292 reaction equation
O1[CH:16]([CH2:17][CH:18]([CH3:20])[CH3:19])[CH2:15][C@@H:14]([CH3:21])[C@@H:13]2[C@@:22]3([CH3:28])[CH2:23][CH2:24][C@@H:25]4[C@:26]5([CH3:27])[CH:6]([CH2:7][CH2:8][C@H:9]4[C@@H:10]3[CH2:11][CH2:12]2)[CH2:5][C@@H:4](O)C[CH:2]15.[N-:30]=[N+:31]=[N-:32].[Na+].[OH2:34].[CH3:35][OH:36]>CS(C)=O>[N:30]([C@@H:2]1[C@@:26]2([CH3:27])[CH:6]([CH2:7][CH2:8][C@@H:9]3[C@@H:25]2[CH2:24][CH2:23][C@@:22]2([CH3:28])[C@H:10]3[CH2:11][CH2:12][C@@H:13]2[C@H:14]([CH3:21])[CH2:15][CH2:16][CH2:17][CH:18]([CH3:19])[CH3:20])[CH2:5][C@@H:4]([OH:34])[C@H:35]1[OH:36])=[N+:31]=[N-:32]

Participants

5

Reactant 3

HCID 33557Sodium AzideHCID 22242641Methanol--water (1/1)HCID 86698319HCID 86698319, compound

Product 1

HCID 86698318HCID 86698318, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

Variant 2: If 2.1 g 1,23-epoxy-cholestane-3β-ol are converted with NaN3 in dimethyl sulfoxide, 1.7 g of colorless crystals are obtained (from water/methanol) with a m.p. of 143-144° C.

Sources & evidence

ORD record
ord-f7ac81abb5694516ae3e7cb18971440b
Source dataset
uspto-grants-2016_07
Patent number
US09382288B2

Reaction notes

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