HCID 66981029, compound → HCID 66981058, compound

Participants

Reaction Steps

A solution 4-(cyclopentylmethyl)-1,2-dimethoxybenzene (7.1 g, 0.032 mol) in 43 ml of hydrobromic acid (48% in water) and 4 ml of acetic acid was heated at 120° C. during 24 hours. The reaction mixture was cooled to room temperature and quenched with 50 ml of NH4Cl solution. The aqueous phase extracted with three 100 ml portions of ether. The ethereal phase was washed with 50 ml of brine and dried over MgSO4. Filtration and concentration gave 6.0 g (97%) of a brownish solid.

Provenance & Evidence