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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1050725Generated: October 26, 2026

1-(2,3-Dichlorophenyl)piperazine → Aripiprazole

https://huagongshe.com/reaction/1050725

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2,3-Dichlorophenyl)piperazineHCID 851833—
Reactant7-(4-bromobutoxy)-3,4-dihydro-2(1H)-quinolinoneHCID 10542064—
ProductAripiprazoleHCID 60795—

Reaction Steps

7-(4-bromobutoxy)-3,4-dihydrocarbostyril, is reacted with 1-(2,3-dichlorophenyl)piperazine and the thus obtained crude aripiprazole crystals are recrystallized from ethanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09387182B2
Source datasetuspto-grants-2016_07
ORD IDord-e61275cfb8e24b7da188d56abee1a0aa
Source noteuspto-grants-2016_07