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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1050762Generated: November 1, 2026

Glycine → {[3-(4-Fluoro-phenyl)-4-hydroxy-7-methyl-isothiazolo[5,4-c]pyridine-5-carbonyl]-amino}-acetic acid

https://huagongshe.com/reaction/1050762

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGlycineHCID 750—
Reactant3-(4-Fluoro-phenyl)-4-hydroxy-7-methyl-isothiazolo[5,4-c]pyridine-5-carboxylic acid ethyl esterHCID 136413576—
Product{[3-(4-Fluoro-phenyl)-4-hydroxy-7-methyl-isothiazolo[5,4-c]pyridine-5-carbonyl]-amino}-acetic acidHCID 135870676—

Reaction Steps

The title compound was synthesized in analogy to Example 1 from 3-(4-Fluoro-phenyl)-4-hydroxy-7-methyl-isothiazolo[5,4-c]pyridine-5-carboxylic acid ethyl ester and glycine: MS (m/z) 360.1 (M−1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09387200B2
Source datasetuspto-grants-2016_07
ORD IDord-2b227fbe321d455c9af161a67cb4fdc2
Source noteuspto-grants-2016_07