Glycine → HCID 135950379, compound

HRID 1050803Notes

Reaction equation

C(O[C:6]([C:8]1[C:9]([OH:24])=[C:10]2[C:22]([CH3:23])=[N:21][S:20][C:11]2=[C:12]([C:14]#[C:15][Si](C)(C)C)[N:13]=1)=[O:7])CCC.[NH2:25][CH2:26][C:27]([OH:29])=[O:28]>>[C:14]([C:12]1[N:13]=[C:8]([C:6]([NH:25][CH2:26][C:27]([OH:29])=[O:28])=[O:7])[C:9]([OH:24])=[C:10]2[C:22]([CH3:23])=[N:21][S:20][C:11]=12)#[CH:15]

Participants

Reactant 2

HCID 750Glycine

HCID 136344058HCID 136344058, compound

Product 1

HCID 135950379HCID 135950379, compound

Procedure

The title compound was synthesized in analogy Example 1 from 4-hydroxy-3-methyl-7-trimethylsilanylethynyl-isothiazolo[5,4-c]pyridine-5-carboxylic acid butyl ester and glycine: MS (m/z) 290.1 (M−1).

Sources & evidence

ORD record: ord-5969b058cac7442d96e30097c565138c
Source dataset: uspto-grants-2016_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09387200B2

Reaction notes

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