Glycine → HCID 135950390, compound

HRID 1050817Notes

Reaction equation

C(O[C:6]([C:8]1[C:9]([OH:20])=[C:10]2[C:18]([CH3:19])=[N:17][S:16][C:11]2=[C:12]([CH2:14][CH3:15])[N:13]=1)=[O:7])CCC.[NH2:21][CH2:22][C:23]([OH:25])=[O:24]>>[CH2:14]([C:12]1[N:13]=[C:8]([C:6]([NH:21][CH2:22][C:23]([OH:25])=[O:24])=[O:7])[C:9]([OH:20])=[C:10]2[C:18]([CH3:19])=[N:17][S:16][C:11]=12)[CH3:15]

Participants

Reactant 2

HCID 750Glycine

HCID 136344068HCID 136344068, compound

Product 1

HCID 135950390HCID 135950390, compound

Procedure

The title compound was synthesized in analogy to Example 1 from 7-Ethyl-4-hydroxy-3-methyl-isothiazolo[5,4-c]pyridine-5-carboxylic acid butyl ester and glycine: MS (m/z) 296.2 (M+1).

Sources & evidence

ORD record: ord-1bd4f7a10cad407585d4fa6a5cd6c09b
Source dataset: uspto-grants-2016_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09387200B2

Reaction notes

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