反应详情

温度

200 °C

1000 g of 1,3-propanediol and 500 g of 2-propyl-1,3-dioxane were combined in a 2 L stainless steel autoclave with 6.0 g of 5% Pd on carbon catalyst. The reactor was sealed and purged twice with N2 and once with H2. The reactor was charged with H2 and heated to 200° C. The reactor was brought to an operating pressure of 6.89 MPa and stirring commenced at 750 rpm. Temperature and pressure were maintained for 2 h. The reactor was cooled, vented, and the contents filtered. The filtrate was analyzed by GC to yield 153 g of 2-propyl-1,3-dioxane, 288 g of 3-BP, 15.9 g of 1,3-dibutoxypropane, and 1017 g of 1,3-propanediol. This corresponds to yield 69% conversion of the acetal and 95% selectivity to the desired ether alcohol, 3-BP.

1. customThe reactor was sealed
2. custompurged twice with N2 and once with H2
3. additionThe reactor was charged with H2
4. temperatureTemperature and pressure were maintained for 2 h
5. temperatureThe reactor was cooled
6. filtrationthe contents filtered