Methyl 3-cyano-5-(trifluoromethoxy)benzoate → 3-Cyano-5-(trifluoromethoxy)benzoic acid

HRID 1051075Notes

Reaction equation

HRID 1051075 reaction equation
[C:1]([C:3]1[CH:4]=[C:5]([CH:10]=[C:11]([O:13][C:14]([F:17])([F:16])[F:15])[CH:12]=1)[C:6]([O:8]C)=[O:7])#[N:2].C(C1C=C(C=C(OC(C)C)C=1)C(O)=O)#N>>[C:1]([C:3]1[CH:4]=[C:5]([CH:10]=[C:11]([O:13][C:14]([F:15])([F:16])[F:17])[CH:12]=1)[C:6]([OH:8])=[O:7])#[N:2]

Participants

3

Reactant 2

HCID 67192787Methyl 3-cyano-5-(trifluoromethoxy)benzoateHCID 671962143-Cyano-5-isopropoxybenzoic acid

Product 1

HCID 219425323-Cyano-5-(trifluoromethoxy)benzoic acid

Procedure

Prepared from methyl 3-cyano-5-(trifluoromethoxy)benzoate according to the procedure for 3-cyano-5-isopropoxybenzoic acid. LCMS-ESI (m/z) calculated for C9H4F3NO3: 231.1; no m/z observed, tR=2.38 min.

Sources & evidence

ORD record
ord-fe1a1ff31d9344d2b02a0f0506c088fe
Source dataset
uspto-grants-2016_07
Patent number
US09388147B2

Reaction notes

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