HCID 66562883, compound → HCID 66562884, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 17.2 mg (30 μmol) 4-{6-[4-(Benzyloxy)phenoxy]-4-[(3,3,3-trifluoropropyl)amino]-1H-benzimidazol-1-yl}-N,2-dimethylbenzamide which was prepared according to example 47 in 0.7 mL ethanol were added 3.19 mg palladium on charcoal (10%) and the mixture was vigorously stirred under an atmosphere of hydrogen for 2 hours at 23° C. After filtration and removal of the solvent the residue was purified by chromatography to give 8.2 mg (54%) of the title compound.

Provenance & Evidence