反应详情

温度

50 °C

A reaction mixture solution prepared by suspending 1.38 g of ethyl 4-methyl-2-[3-nitro-4-(propan-2-yloxy)phenyl]-1,3-thiazole-5-carboxylate in 15 mL of ethanol and adding 100 mg of palladium/carbon (10 wt %) to the suspension was heated under stirring at 50° C. for 14 hours under a hydrogen atmosphere. The reaction mixture solution was celite-filtered and the filtrate was concentrated under reduced pressure to obtain 1.26 g of ethyl 2-[3-amino-4-(propan-2-yloxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylate.

1. customA reaction mixture solution prepared
2. temperaturewas heated
3. filtrationThe reaction mixture solution was celite-filtered
4. concentrationthe filtrate was concentrated under reduced pressure