HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-5-methoxy-2-methyl-1,2,3,4-tetrahydroquinoline → (S)-8-Fluoro-5-methoxy-2-methyl-1,2,3,4-tetrahydroquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-5-methoxy-2-methyl-1,2,3,4-tetrahydroquinoline | HCID 118075405 | — |
| Reactant | 8-Fluoro-5-methoxy-2-methylquinoline | HCID 118075821 | — |
| Product | (S)-8-Fluoro-5-methoxy-2-methyl-1,2,3,4-tetrahydroquinoline | HCID 118075452 | — |
Reaction Steps
(S)-8-Fluoro-5-methoxy-2-methyl-1,2,3,4-tetrahydroquinoline was synthesized from 8-fluoro-5-methoxy-2-methylquinoline according to the procedures described above for (2S)-5-methoxy-2-methyl-1,2,3,4-tetrahydroquinoline (Intermediate 1). MS (ESI, pos. ion) m/z 196 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09388161B2 |
| Source dataset | uspto-grants-2016_07 |
| ORD ID | ord-be0fbc6823274d24a14f0efeb4b7a00b |
| Source note | uspto-grants-2016_07 |