HCID 78164042, compound → HCID 71735403, compound

HRID 1051890Notes

Reaction equation

HRID 1051890 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:9]=[C:10]([N:23]3[CH2:28][CH:27]([CH3:29])[CH2:26][CH:25]([CH3:30])[CH2:24]3)[S:11][C:12]=2[C:13]2[CH:18]=[CH:17][C:16]([S:19]([NH2:22])(=[O:21])=[O:20])=[CH:15][CH:14]=2)=[CH:4][CH:3]=1>CO>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:9]=[C:10]([N:23]3[CH2:28][C@H:27]([CH3:29])[CH2:26][C@H:25]([CH3:30])[CH2:24]3)[S:11][C:12]=2[C:13]2[CH:14]=[CH:15][C:16]([S:19]([NH2:22])(=[O:20])=[O:21])=[CH:17][CH:18]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 1

HCID 78164042HCID 78164042, compound2×

Product 1

HCID 71735403HCID 71735403, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

(trans +) 4-(4-(4-chlorophenyl)-2-(3,5-dimethylpiperidin-1-yl)thiazol-5-yl)benzenesulfonamide (Compound 7). [α]23D: 32.32 (c=1.0, MeOH). MS: m/z 462 (M+1).

Sources & evidence

ORD record
ord-d5c46f2da3e74570a4a52fd63d879d37
Source dataset
uspto-grants-2016_07
Patent number
US09388196B2

Reaction notes

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