HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Toluenesulfonic acid → HCID 90303245, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | HCID 90303551 | HCID 90303551 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | Oxolane--water (1/1) | HCID 21881883 | — |
| Product | HCID 90303245 | HCID 90303245 | — |
Reaction Steps
A soln. of 7-((tetrahydro-2H-pyran-2-yl)oxy)-6,7-dihydro-5H-pyrano[2,3-d]thiazole (895 mg, 3.71 mmol) and PTSA (141 mg, 0.74 mmol) in THF/H2O (7.4 mL, 1:1) was stirred at RT overnight. The mixture was diluted with DCM, dried over Na2SO4, and conc. in vacuo. Purification by means of CC (40-100% EtOAc/Hept) provided a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09388197B2 |
| Source dataset | uspto-grants-2016_07 |
| ORD ID | ord-411b379e4f4f4587a1779635d0bb52dc |
| Source note | uspto-grants-2016_07 |