HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Methylthio)-6,7-dihydro-5H-pyrrolo[3,4-D]pyrimidine → 4-(2-Methylsulfanyl-5,7-dihydro-pyrrolo[3,4-d]pyrimidin-6-yl)-pyridine-2-carboxylic acid (3-isopropyl-phenyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Methylthio)-6,7-dihydro-5H-pyrrolo[3,4-D]pyrimidine | HCID 67065848 | — |
| Reactant | 4-bromo-N-(3-isopropylphenyl)picolinamide | HCID 86695852 | — |
| Product | 4-(2-Methylsulfanyl-5,7-dihydro-pyrrolo[3,4-d]pyrimidin-6-yl)-pyridine-2-carboxylic acid (3-isopropyl-phenyl)-amide | HCID 86695856 | — |
Reaction Steps
In a manner similar to that describe in Example 126, 2-(methylthio)-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine and 4-bromo-N-(3-isopropylphenyl)picolinamide were converted to the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09388176B2 |
| Source dataset | uspto-grants-2016_07 |
| ORD ID | ord-1fb0d1e1d82e41e8b63fdd7e4f9d5576 |
| Source note | uspto-grants-2016_07 |