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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1052047Generated: November 2, 2026

3-Bromo-3'-(trifluoromethyl)benzanilide → 3-[2-(methylthio)-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidin-6-yl]-N-[3-(trifluoromethyl)phenyl]benzamide

https://huagongshe.com/reaction/1052047

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Bromo-3'-(trifluoromethyl)benzanilideHCID 763883—
Reactant2-(Methylthio)-6,7-dihydro-5H-pyrrolo[3,4-D]pyrimidineHCID 67065848—
Product3-[2-(methylthio)-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidin-6-yl]-N-[3-(trifluoromethyl)phenyl]benzamideHCID 71735689—

Reaction Steps

In a manner similar to that describe in Example 126, 2-(methylthio)-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine and 3-Bromo-N-[3-(trifluoromethyl)phenyl]benzamide were converted to the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09388176B2
Source datasetuspto-grants-2016_07
ORD IDord-cb20b80f172c4f959ce54544b6454112
Source noteuspto-grants-2016_07