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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1052054Generated: October 26, 2026

3-(Trifluoromethyl)aniline → 3-Bromo-5-methyl-N-[3-(trifluoromethyl)phenyl]benzamide

https://huagongshe.com/reaction/1052054

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Trifluoromethyl)anilineHCID 7375—
Reactant3-Bromo-5-methylbenzoic acidHCID 3433127—
Product3-Bromo-5-methyl-N-[3-(trifluoromethyl)phenyl]benzamideHCID 8669585958%

Reaction Steps

In a manner similar to that described in Preparation 41, 3-bromo-5-methylbenzoic acid (400 mg) and 3-(trifluoromethyl)aniline were converted to the title compound (388 mg, 58%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09388176B2
Source datasetuspto-grants-2016_07
ORD IDord-c18beda9b0cd454997d76b44b1a14ffa
Source noteuspto-grants-2016_07