3-(Trifluoromethyl)aniline → HCID 977755, compound

HRID 1052061Notes

Reaction equation

HRID 1052061 reaction equation
[Br:1][C:2]1[CH:3]=[N:4][CH:5]=[C:6]([CH:10]=1)[C:7]([OH:9])=O.[F:11][C:12]([F:21])([F:20])[C:13]1[CH:14]=[C:15]([CH:17]=[CH:18][CH:19]=1)[NH2:16]>>[Br:1][C:2]1[CH:3]=[N:4][CH:5]=[C:6]([CH:10]=1)[C:7]([NH:16][C:15]1[CH:17]=[CH:18][CH:19]=[C:13]([C:12]([F:11])([F:20])[F:21])[CH:14]=1)=[O:9]

Participants

3

Reactant 2

HCID 73753-(Trifluoromethyl)anilineHCID 887075-Bromonicotinic acid

Product 1

HCID 977755HCID 977755, compound

Procedure

In a manner similar to that described in Preparation 17, 5-bromonicotinic acid and 3-trifluoromethylaniline were converted to the title compound

Sources & evidence

ORD record
ord-ba79339a717f4e91a0ea6a0e36f75d42
Source dataset
uspto-grants-2016_07
Patent number
US09388176B2

Reaction notes

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