HCID 9293365, compound → HCID 86695864, compound

HRID 1052064Notes

Reaction equation

HRID 1052064 reaction equation
[CH3:1][S:2][C:3]1[N:4]=[CH:5][C:6]2[CH2:12][NH:11][CH2:10][CH2:9][C:7]=2[N:8]=1.Br[C:14]1[CH:15]=[N:16][CH:17]=[C:18]([CH:31]=1)[C:19]([NH:21][C:22]1[CH:27]=[CH:26][CH:25]=[C:24]([CH:28]([CH3:30])[CH3:29])[CH:23]=1)=[O:20]>>[CH:28]([C:24]1[CH:23]=[C:22]([NH:21][C:19](=[O:20])[C:18]2[CH:31]=[C:14]([N:11]3[CH2:10][CH2:9][C:7]4[N:8]=[C:3]([S:2][CH3:1])[N:4]=[CH:5][C:6]=4[CH2:12]3)[CH:15]=[N:16][CH:17]=2)[CH:27]=[CH:26][CH:25]=1)([CH3:30])[CH3:29]

Participants

3

Reactant 2

HCID 9293365HCID 9293365, compoundHCID 552636702-(Methylthio)-5,6,7,8-tetrahydropyrido[4,3-D]pyrimidine

Product 1

HCID 86695864HCID 86695864, compound

Procedure

In a manner similar to that described for Example 138, 2-(methylsulfanyl)-5,6,7,8-tetrahydropyrido[4,3-d]-pyrimidine and 5-bromo-N-(3-isopropylphenyl)nicotinamide were converted to the title compound.

Sources & evidence

ORD record
ord-f4daed6bb8de4bc8ab99088bd89bb86b
Source dataset
uspto-grants-2016_07
Patent number
US09388176B2

Reaction notes

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