1H-Pyrazolo[3,4-c]pyridine-1-acetic acid, 3-(aminocarbonyl)- → 2-(3-Carbamoyl-5-(pyrimidin-2-ylmethoxy)-1H-indazol-1-yl)acetic acid

Participants

Reaction Steps

The title compound was prepared from tert-butyl 2-(3-cyano-5-(pyrimidin-2-ylmethoxy)-1H-indazol-1-yl)acetate in a similar manner as described in step D of Scheme A6 for the preparation of 2-(3-carbamoyl-1H-pyrazolo[3,4-c]pyridin-1-yl)acetic acid. MS (LC-MS): 328.2 [M+H]+, 326.3 [M−H]−, tR (HPLC conditions e): 2.77 min.

Provenance & Evidence