1-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperazine → 2-(3,5-Dimethoxyphenethyl)-6-(3-(piperazin-1-yl)phenyl)-5H-pyrrolo[2,3-b]pyrazine

Participants

Role	Name	HCID	Charge
Reactant	1-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperazine	HCID 45052228	—
Reactant	6-Bromo-2-[2-(3,5-dimethoxyphenyl)ethyl]-5H-pyrrolo[2,3-b]pyrazine	HCID 89962437	—
Product	2-(3,5-Dimethoxyphenethyl)-6-(3-(piperazin-1-yl)phenyl)-5H-pyrrolo[2,3-b]pyrazine	HCID 73053963	—

Reaction Steps

The compound was prepared by using procedures analogous to those described for the synthesis of Example 53, Step 2 starting from 6-bromo-2-[2-(3,5-dimethoxyphenyl)ethyl]-5H-pyrrolo[2,3-b]pyrazine and 1-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]piperazine. LCMS calculated for C26H30N5O2(M+H)+: m/z=444.2. Found 444.2.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US09388185B2
Source dataset	uspto-grants-2016_07
ORD ID	ord-a7740863d7d449d0aa4afa622437d4f9
Source note	uspto-grants-2016_07