Hexamethylene diisocyanate → HCID 87529804, compound

Participants

Reaction Conditions

Reaction Steps

A three-neck flask equipped with a condenser, a dropping funnel and a thermocouple and placed on a mantle heater, was charged with 50 g (0.4 mole) of 1-(3-aminopropyl)imidazole and 250 mL of acetonitrile. Then, the solution mixture was heated to 70 to 80° C. To the solution mixture, 33.6 g (0.2 mole) of hexamethylene diisocyanate dissolved in 50 mL of acetonitrile was added dropwise to generate a white precipitate. After completion of addition, the mixture was stirred at 70 to 80° C. for one hour and then cooled to room temperature. The white solid substance was filtered and washed with acetonitrile to obtain an imidazole-isocyanate adduct (hereinafter simply referred to as A-1).

Provenance & Evidence