Boron tribromide → HCID 90102841, compound

Participants

Reaction Steps

N-(3-Bromo-5-fluorophenyl)-4-methoxybenzenesulfonamide (507 mg, 1.41 mmol) was treated with boron tribromide (1M in dichloromethane, 7.0 ml, 7 mmol) using dichloromethane (10 ml) as a solvent according to the method described in Example 23. The resulting crude was purified by flash chromatography using SP1® Purification System (0% to 40%, dichloromethane-ethyl acetate) to obtain 480 mg (99% yield) of the title compound. Purity: 100%

Provenance & Evidence