Methanesulfonyl chloride → HCID 89773712, compound

HRID 1052579Notes

Reaction equation

[Br:1][C:2]1[CH:3]=[C:4]([CH:6]=[C:7]([CH3:9])[CH:8]=1)[NH2:5].[CH3:10][S:11](Cl)(=[O:13])=[O:12]>>[Br:1][C:2]1[CH:3]=[C:4]([NH:5][S:11]([CH3:10])(=[O:13])=[O:12])[CH:6]=[C:7]([CH3:9])[CH:8]=1

Participants

Reactant 2

HCID 31297Methanesulfonyl chloride

HCID 30185263-Bromo-5-methylaniline

Product 1

HCID 89773712HCID 89773712, compoundYield 99.3%

Procedure

3-Bromo-5-(methyl)aniline (2 g, 10.75 mmol) was treated with methanesulfonyl chloride (915 μl, 11.82 mmol) according to the method described in Preparation 15b to give 2.82 g (96% yield) of the title compound. Purity 95%.

Sources & evidence

ORD record: ord-17a14e9c1eae4d8a94f4566abfd747cb
Source dataset: uspto-grants-2016_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09388189B2

Reaction notes

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