Ethyl Acetate → HCID 90102989, compound

Participants

Reaction Steps

5-Bromo-2-chloropyridin-3-amine (1.5 g, 7.23 mmol) was dissolved in dichloromethane (30 ml). Diisopropylethylamine (1.52 ml, 8.67 mmol) first and then a solution of 3-methoxybenzoyl chloride (1.08 ml, 7.95 mmol) in dichloromethane (20 ml) were added. After 1 h at room temperature the reaction mixture was diluted with ethyl acetate and washed with water and brine, dried over sodium sulphate, filtered and evaporated under reduced pressure to give 2.8 g (92% yield) of the title compound. Purity 81%.

Provenance & Evidence