Boron tribromide → HCID 73775797, compound

Participants

Reaction Steps

(S)-4-Amino-6-((1-(5-(3-methoxybenzyl)-4-oxo-3-phenyl-3,4-dihydropyrrolo[2,1-f][1,2,4]triazin-2-yl)ethyl)amino)pyrimidine-5-carbonitrile (72 mg, 0.15 mmol) was treated with boron tribromide (1M in dichloromethane, 580 μl, 0.58 mmol) with dichloromethane as a solvent according to the method described in Example 23. The residue was purified by reverse phase using SP1® Purification System to give 27 mg (39% yield) as a solid. Purity 98%.

Provenance & Evidence