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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 105280Generated: October 30, 2026

Diethyl Ether → 4-(4-Chloro-2-fluorophenoxy)-7-(3-(1,1-dioxothiomorpholino)propoxy)-6-methoxyquinazoline

https://huagongshe.com/reaction/105280

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl EtherHCID 3283—
ReactantDichloromethaneHCID 6344—
ReactantTributylphosphineHCID 13831—
Reactant1,1'-(Azodicarbonyl)dipiperidineHCID 73042—
Reactant4-(3-Hydroxypropyl)thiomorpholine 1,1-DioxideHCID 11435473—
Reactant4-(4-Chloro-2-fluorophenoxy)-7-hydroxy-6-methoxyquinazolineHCID 135616204—
Product4-(4-Chloro-2-fluorophenoxy)-7-(3-(1,1-dioxothiomorpholino)propoxy)-6-methoxyquinazolineHCID 21935999—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-10e6927d72cf4401b9deec9818614582
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)