HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(Difluoromethoxy)-4-isocyanatobenzene → HCID 58329417, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(Difluoromethoxy)-4-isocyanatobenzene | HCID 2733371 | — |
| Reactant | 4-Cyclopentylamino-8-methoxy-quinoline-3-carboxylic acid ethyl ester | HCID 67249718 | — |
| Product | HCID 58329417 | HCID 58329417 | 41.9% |
Reaction Steps
1-Cyclopentyl-3-(4-difluoromethoxy-phenyl)-7-methoxy-1H-pyrimido[5,4-c]quinoline-2,4-dione (19 mg) was prepared from 4-cyclopentylamino-8-methoxy-quinoline-3-carboxylic acid ethyl ester (0.1 mmol) and 1-difluoromethoxy-4-isocyanato-benzene (0.5 mmol) following general procedure C. LCMS: m/z 454 [M+1]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09393245B2 |
| Source dataset | uspto-grants-2016_07 |
| ORD ID | ord-e4553247df6f415ba6f8dda0ed2cf2fd |
| Source note | uspto-grants-2016_07 |