HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 135741236, compound → 2-methyl-2-propanyl {[4-({(2S,4R)-2-(4-chloro-5-{4-[(methoxycarbonyl)amino]phenyl}-1H-imidazol-2-yl)-4-[1-(methylsulfonyl)-4-piperidinyl]-1-pyrrolidinyl}carbonyl)phenyl](imino)methyl}carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 135741236 | HCID 135741236 | — |
| Reactant | methyl [4-(4-chloro-2-{(2S,4R)-4-[1-(methylsulfonyl)-4-piperidinyl]-2-pyrrolidinyl}-1H-imidazol-5-yl)phenyl]carbamate hydrochloride | HCID 178501961 | — |
| Product | 2-methyl-2-propanyl {[4-({(2S,4R)-2-(4-chloro-5-{4-[(methoxycarbonyl)amino]phenyl}-1H-imidazol-2-yl)-4-[1-(methylsulfonyl)-4-piperidinyl]-1-pyrrolidinyl}carbonyl)phenyl](imino)methyl}carbamate | HCID 178501956 | — |
Reaction Steps
The compound prepared in Example 67 was treated with the compound prepared in Example 18 following the procedure described in Example 8 to give the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09394250B2 |
| Source dataset | uspto-grants-2016_07 |
| ORD ID | ord-30660a600a06455dabd1d8736f18abc9 |
| Source note | uspto-grants-2016_07 |