1H-Benzimidazole, 2-chloro-7-iodo-5-(trifluoromethyl)- → [5-chloro-6-[4-[4-iodo-6-(trifluoromethyl)-1H-benzimidazol-2-yl]-3-methylpiperazin-1-yl]-3-pyridinyl]methanol

HRID 105392Notes

Reaction equation

HRID 105392 reaction equation
[Cl:17][c:18]1[n:19][c:20]2[c:21]([nH:22]1)[cH:23][c:24]([C:28]([F:29])([F:30])[F:31])[cH:25][c:26]2[I:27].[Cl:1][c:2]1[cH:3][c:4]([CH2:15][OH:16])[cH:5][n:6][c:7]1[N:8]1[CH2:9][CH:10]([CH3:14])[NH:11][CH2:12][CH2:13]1>>[Cl:1][c:2]1[cH:3][c:4]([CH2:15][OH:16])[cH:5][n:6][c:7]1[N:8]1[CH2:9][CH:10]([CH3:14])[N:11]([c:18]2[nH:19][c:20]3[c:21]([n:22]2)[cH:23][c:24]([C:28]([F:29])([F:30])[F:31])[cH:25][c:26]3[I:27])[CH2:12][CH2:13]1

Participants

3

Reactant 2

HCID 674014061H-Benzimidazole, 2-chloro-7-iodo-5-(trifluoromethyl)-HCID 69216273[5-Chloro-6-(3-methylpiperazin-1-yl)-3-pyridinyl]methanol

Product 1

HCID 178430131[5-chloro-6-[4-[4-iodo-6-(trifluoromethyl)-1H-benzimidazol-2-yl]-3-methylpiperazin-1-yl]-3-pyridinyl]methanol

Sources & evidence

ORD record
ord-f9b4319061124c9d8343b8abf806fcbd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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