Sodium ion → (1-(1-(5-Ethylpyrimidin-2-yl)piperidin-4-yl)-3-(trifluoromethyl)-1H-pyrazol-4-yl)methanol

HRID 105394Notes

Reaction equation

HRID 105394 reaction equation
[BH4-:29].[CH2:1]([CH3:2])[c:3]1[cH:4][n:5][c:6]([N:9]2[CH2:10][CH2:11][CH:12]([n:15]3[n:16][c:17]([C:25]([F:26])([F:27])[F:28])[c:18]([C:20](=[O:21])[O:22][CH2:23][CH3:24])[cH:19]3)[CH2:13][CH2:14]2)[n:7][cH:8]1.[Na+:30]>>[CH2:1]([CH3:2])[c:3]1[cH:4][n:5][c:6]([N:9]2[CH2:10][CH2:11][CH:12]([n:15]3[n:16][c:17]([C:25]([F:26])([F:27])[F:28])[c:18]([CH2:20][OH:21])[cH:19]3)[CH2:13][CH2:14]2)[n:7][cH:8]1

Participants

4

Reactant 3

HCID 923Sodium ionHCID 28123BorohydrideHCID 57708415ethyl 1-(1-(5-ethylpyrimidin-2-yl)piperidin-4-yl)-3-(trifluoromethyl)-1H-pyrazole-4-carboxylate

Product 1

HCID 57708394(1-(1-(5-Ethylpyrimidin-2-yl)piperidin-4-yl)-3-(trifluoromethyl)-1H-pyrazol-4-yl)methanol

Sources & evidence

ORD record
ord-2238fc65fd26460fbe773171956e8c7b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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