2-Chloroethyl isocyanate → ethyl 4-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)thiazole-5-carboxylate

HRID 105401Notes

Reaction equation

HRID 105401 reaction equation
[Cl:1][CH2:2][CH2:3][N:4]=[C:5]=[O:6].[Cl:7][CH2:8][CH2:9][CH2:10][N:11]=[C:12]=[O:13].[NH2:14][c:15]1[s:16][c:17]([C:21](=[O:22])[O:23][CH2:24][CH3:25])[c:18]([CH3:20])[n:19]1>>[CH2:8]1[CH2:9][CH2:10][NH:11][C:12](=[O:13])[N:14]1[c:15]1[s:16][c:17]([C:21](=[O:22])[O:23][CH2:24][CH3:25])[c:18]([CH3:20])[n:19]1

Participants

4

Reactant 3

HCID 160352-Chloroethyl isocyanateHCID 166752Propane, 1-chloro-3-isocyanato-HCID 343747Ethyl 2-amino-4-methylthiazole-5-carboxylate

Product 1

HCID 58031510ethyl 4-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)thiazole-5-carboxylate

Sources & evidence

ORD record
ord-42770a9fa3b943fb90a0d9f94644605a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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