Imidazole → HCID 62918897, compound

Participants

Reaction Steps

Synthesized from 4a (600 mg, 3.04 mmol), imidazole (829 mg, 12.1 mmol) and K2CO3 (2.07 g, 15.0 mmol) in DMF according to Method A. Yield: 476 mg, 2.58 mmol, 85%. 1H NMR (CDCl3, 500 MHz): δH (ppm): 5.41 (s, 2H), 6.97 (t, J=1.3 Hz, 1H), 7.15 (t, J=1.3 Hz, 1H), 7.36-7.38 (m, 1H), 7.51 (dd, J=8.2, 4.7 Hz, 1H), 7.63 (s, 1H), 8.68 (dd, J=4.7, 1.6 Hz, 1H); 13C NMR (CDCl3, 125 MHz): δC (ppm)=47.1, 115.3, 119.1, 127.4, 130.9, 132.5, 135.6, 137.0, 137.5, 150.7; MS (ESI): m/z=185.08 [M+H]+.

Provenance & Evidence