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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1054219Generated: November 4, 2026

Cesium carbonate → HCID 1486319, compound

https://huagongshe.com/reaction/1054219

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCesium carbonateHCID 10796—
Reactant1-(Bromomethyl)-4-(trifluoromethyl)benzeneHCID 123062—
ReactantHCID 22026242HCID 22026242—
SolventWaterHCID 962—
SolventDimethylformamideHCID 6228—
ProductHCID 1486319HCID 148631987%

Reaction Steps

To a stirring solution of N-hydroxy phthalamide (5.25 g, 32.3 mmol) in DMF (30 mL) was added cesium carbonate (15.80 g, 48.5 mmol) and 1-(bromomethyl)-4-(trifluoromethyl)benzene (5 ml, 32.3 mmol) at RT. Reaction mixture was stirred for 3 h. and then diluted with water. Precipitated product was filtered and dried to get titled compound in 87% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09394300B2
Source datasetuspto-grants-2016_07
ORD IDord-641e30f8687041909a4347fa07bab6f7
Source noteuspto-grants-2016_07