2H-Pyran-4-carboxylic acid, tetrahydro-, methyl ester → HCID 58994993, compound

HRID 1054285Notes

Reaction equation

HRID 1054285 reaction equation
[CH3:1][O:2][C:3]([CH:5]1[CH2:10][CH2:9][O:8][CH2:7][CH2:6]1)=[O:4].Br[C:12]1[CH:13]=[CH:14][C:15]([N+:25]([O-:27])=[O:26])=[C:16]([N:18]2[CH2:23][CH2:22][CH:21]([CH3:24])[CH2:20][CH2:19]2)[CH:17]=1>>[CH3:1][O:2][C:3]([C:5]1([C:12]2[CH:13]=[CH:14][C:15]([N+:25]([O-:27])=[O:26])=[C:16]([N:18]3[CH2:23][CH2:22][CH:21]([CH3:24])[CH2:20][CH2:19]3)[CH:17]=2)[CH2:10][CH2:9][O:8][CH2:7][CH2:6]1)=[O:4]

Participants

3

Reactant 2

HCID 27735202H-Pyran-4-carboxylic acid, tetrahydro-, methyl esterHCID 59794652HCID 59794652, compound

Product 1

HCID 58994993HCID 58994993, compound

Procedure

The title compound is prepared by the procedure of Example 16, step (a) using tetrahydro-pyran-4-carboxylic acid methyl ester and 1-(5-bromo-2-nitro-phenyl)-4-methyl-piperidine (US 2005131022 A1).

Sources & evidence

ORD record
ord-5cdc4bb42c994251b0cf23066984d496
Source dataset
uspto-grants-2016_07
Patent number
US09394289B2

Reaction notes

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