Methanol → 4-{5-(1-Hydroxyethyl)-6-methyl-2-thioxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydro-4-pyrimidinyl}benzonitrile
Reaction equation
[BH4-:30].[C:1]([CH3:2])(=[O:3])[C:4]1=[C:9]([CH3:10])[N:8]([c:11]2[cH:12][c:13]([C:17]([F:18])([F:19])[F:20])[cH:14][cH:15][cH:16]2)[C:7](=[S:21])[NH:6][CH:5]1[c:22]1[cH:23][cH:24][c:25]([C:26]#[N:27])[cH:28][cH:29]1.[CH3:32][OH:33].[Na+:31]>>[CH:1]([CH3:2])([OH:3])[C:4]1=[C:9]([CH3:10])[N:8]([c:11]2[cH:12][c:13]([C:17]([F:18])([F:19])[F:20])[cH:14][cH:15][cH:16]2)[C:7](=[S:21])[NH:6][CH:5]1[c:22]1[cH:23][cH:24][c:25]([C:26]#[N:27])[cH:28][cH:29]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-9931d18efb354c33882514999bc52e69
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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