Dichloromethane → 1,1-Dimethylethyl 3-[2-(2-{[(4-bromo-2-fluorophenyl)amino]carbonyl}hydrazino)-2-oxoethyl]-1-azetidinecarboxylate

HRID 105486Notes

Reaction equation

HRID 105486 reaction equation
[Br:17][c:18]1[cH:19][c:20]([F:27])[c:21]([N:24]=[C:25]=[O:26])[cH:22][cH:23]1.[Cl:28][CH2:29][Cl:30].[NH:1]([NH2:2])[C:3]([CH2:4][CH:5]1[CH2:6][N:7]([C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[CH2:8]1)=[O:16]>>[NH:1]([NH:2][C:25]([NH:24][c:21]1[c:20]([F:27])[cH:19][c:18]([Br:17])[cH:23][cH:22]1)=[O:26])[C:3]([CH2:4][CH:5]1[CH2:6][N:7]([C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[CH2:8]1)=[O:16]

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 27333654-Bromo-2-fluorophenyl isocyanateHCID 67355105Tert-butyl 3-(2-hydrazinyl-2-oxoethyl)azetidine-1-carboxylate

Product 1

HCID 673536431,1-Dimethylethyl 3-[2-(2-{[(4-bromo-2-fluorophenyl)amino]carbonyl}hydrazino)-2-oxoethyl]-1-azetidinecarboxylate

Sources & evidence

ORD record
ord-a18a75fdd4d34e3ca645beedbfb52a12
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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