反应详情

Was prepared in the same manner as described in General Procedure Example 1g) using 1-methyl-5-(pyrrolidin-1-yl)-1H-1,2,4-triazole-3-carbaldehyde (45 mg, 250 μmol, Eq: 1.00) and ((5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)methyl)triphenylphosphonium chloride (115 mg, 250 μmol, Eq: 1.00) as starting materials. Chromatography afforded 5,8-Dimethyl-2-[2-(1-methyl-5-pyrrolidin-1-yl-1H-[1,2,4]triazol-3-yl)-vinyl]-[1,2,4]triazolo[1,5-a]pyrazine (32 mg, 39.5%) as white solid. MS: m/z=325.5 (M+H+)

1. customWas prepared in the same manner