HCID 53236067, compound → 2-(2-(3-bromo-1-(4-methoxybenzyl)-1H-1,2,4-triazol-5-yl)vinyl)-5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazine

Participants

Reaction Steps

Was prepared in the same manner as described in General Procedure Example 1g) using 3-bromo-1-(4-methoxybenzyl)-1H-1,2,4-triazole-5-carbaldehyde (50 mg, 169 μmol, Eq: 1.00) and ((5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)methyl)triphenylphosphonium chloride (77.5 mg, 169 μmol, Eq: 1.00) as starting materials. Chromatography afforded 2-{2-[5-Bromo-2-(4-methoxy-benzyl)-2H-[1,2,4]triazol-3-yl]-vinyl}-5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazine (50 mg, 35.4%) as a white solid. MS: m/z=442.3 (M+H+)

Provenance & Evidence