Pyrrolidine → HCID 123856582, compound

Participants

Reaction Steps

Was prepared in the same manner as described in General Procedure Example 9 using 2-(2-(3-bromo-1-(4-methoxybenzyl)-1H-1,2,4-triazol-5-yl)vinyl)-5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazine (55 mg, 125 μmol, Eq: 1.00) and pyrrolidine (17.8 mg, 20.7 μl, 250 μmol, Eq: 2) as starting materials. Chromatography afforded 2-{2-[2-(4-Methoxy-benzyl)-5-pyrrolidin-1-yl-2H-[1,2,4]triazol-3-yl]-vinyl}-5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazine (23 mg, 42.8%) as a light yellow solid. MS: m/z=431.5 (M+H+)

Provenance & Evidence