HCID 90071562, compound → HCID 83891736, compound

Participants

Reaction Steps

(E)-Benzyl 3-(1-methyl-3-(pyrrolidin-1-yl)-1H-1,2,4-triazol-5-yl)acrylate was stirred with palladium on carbon (10 wt %, 140 mg) in dioxane (60 ml) under hydrogen for 2 h. Additional palladium on carbon (10 wt %, 250 mg) was added and the mixture was stirred overnight under hydrogen. The mixture was filtered over Celite and concentrated to give the product (1.95 g, 96.7%) as a white solid. MS: m/z=225.2 (M+H+).

Provenance & Evidence