反应详情

Was prepared in the same manner as described in Example 49e) using ((5,8-dimethyl-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)methyl)triphenylphosphonium chloride (350 mg, 763 μmol, Eq: 1.00) and 1-methyl-3-(2-methylpyrrolidin-1-yl)-1H-1,2,4-triazole-5-carbaldehyde (148 mg, 763 μmol, Eq: 1.00) affording 5,8-dimethyl-2-{(E)-2-[2-methyl-5-(2-methyl-pyrrolidin-1-yl)-2H-[1,2,4]triazol-3-yl]-vinyl}-[1,2,4]triazolo[1,5-c]pyrimidine (190 mg, 73.6%) as a bright yellow solid. MS: m/z=339.5 (M+H+)

1. customWas prepared in the same manner