Hexylamine → 15210-87-4

HRID 1055191Notes

Reaction equation

HRID 1055191 reaction equation
[CH2:1]([NH2:7])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].[CH2:8]=[C:9]1[O:13][C:11](=[O:12])[CH2:10]1>CO.CCCCCC>[CH2:1]([NH:7][C:11](=[O:12])[CH2:10][C:9](=[O:13])[CH3:8])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]

Participants

5

Reactant 2

HCID 8102HexylamineHCID 12661Diketene

Product 1

HCID 1292095715210-87-4Yield 51.1%

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 8058HexaneSolvent

Conditions

Temperature
0 °C

Procedure

A solution of 27.83 g (0.28 mol) N-n-hexylamine was added dropwise to a solution of 20.00 g (0.24) diketene in 100 ml MeOH at 0° C. After stirring for 4 hours at 0° C., no starting material was detected anymore by thin-layer chromatography. The reaction mixture was spun off, and the obtained solid was taken up in 200 ml n-hexane, filtrated off and dried overnight under vacuum. 22.53 g of product was obtained as a white solid.

Workup

  1. filtrationfiltrated off
  2. customdried overnight under vacuum

Sources & evidence

ORD record
ord-8a78432b741e4199937feafec3a6aa03
Source dataset
uspto-grants-2016_07
Patent number
US09394324B2

Reaction notes

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