HCID 10516606, compound → HCID 89699939, compound

HRID 1055639Notes

Reaction equation

HRID 1055639 reaction equation
C(O[CH:4](OCC)[CH2:5][N:6]1[C:10]([NH2:11])=[CH:9][C:8]([C:12]2[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=2)=[N:7]1)C.Br[C:22]1[CH:27]=[C:26]([N+:28]([O-])=O)[C:25]([CH3:31])=[CH:24][C:23]=1[CH3:32]>>[CH3:31][C:25]1[C:24]([N:11]2[C:10]3[N:6]([N:7]=[C:8]([C:12]4[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=4)[CH:9]=3)[CH:5]=[CH:4]2)=[C:23]([CH3:32])[CH:22]=[CH:27][C:26]=1[NH2:28]

Participants

3

Reactant 2

HCID 10516606HCID 10516606, compoundHCID 124743261-Bromo-2,4-dimethyl-5-nitrobenzene

Product 1

HCID 89699939HCID 89699939, compound

Procedure

200 mg (0.72 mmol) of the compound of Example 4A together with 200 mg (0.87 mmol) of 1-bromo-2,4-dimethyl-5-nitrobenzene were reacted and worked up analogously to the procedure of Example 10A/Step 1. This gave 200 mg (86% pure, 56% of theory) of the title compound.

Sources & evidence

ORD record
ord-44fc9034fc774733be20a2b505a1b6a2
Source dataset
uspto-grants-2016_07
Patent number
US09394309B2

Reaction notes

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