2-Bromo-1-chloro-4-nitrobenzene → HCID 89700356, compound

Participants

Reaction Steps

Analogously to the process described in Example 9A/Step 1, 1.0 g (3.62 mmol) of the compound of Example 4A and 941 mg (3.98 mmol) of 1-bromo-2-chloro-5-nitrobenzene gave 1.26 g (80% of theory) of the title compound. In this case, the reaction time in the microwave reactor was 1 h at a temperature of 140° C. Chromatographic isolation of the product was by MPLC (mobile phase cyclohexane/ethyl acetate 1:2).

Provenance & Evidence