2-Bromo-6-nitrotoluene → HCID 89699584, compound

HRID 1055682Notes

Reaction equation

HRID 1055682 reaction equation
[CH2:1]([O:3][CH:4]([O:18][CH2:19][CH3:20])[CH2:5][N:6]1[C:10]([NH2:11])=[CH:9][C:8]([C:12]2[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=2)=[N:7]1)[CH3:2].Br[C:22]1[CH:27]=[CH:26][CH:25]=[C:24]([N+:28]([O-:30])=[O:29])[C:23]=1[CH3:31]>>[CH2:1]([O:3][CH:4]([O:18][CH2:19][CH3:20])[CH2:5][N:6]1[C:10]([NH:11][C:22]2[CH:27]=[CH:26][CH:25]=[C:24]([N+:28]([O-:30])=[O:29])[C:23]=2[CH3:31])=[CH:9][C:8]([C:12]2[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=2)=[N:7]1)[CH3:2]

Participants

3

Reactant 2

HCID 1235372-Bromo-6-nitrotolueneHCID 10516606HCID 10516606, compound

Product 1

HCID 89699584HCID 89699584, compound

Procedure

Analogously to the process described in Example 64A/Step 1, 1.0 g (3.62 mmol) of the compound of Example 4A and 860 mg (3.98 mmol) of 2-bromo-6-nitrotoluene gave 1.45 g (97% of theory) of the title compound.

Sources & evidence

ORD record
ord-568f0f641b6a46dc897dd3f862b29d0b
Source dataset
uspto-grants-2016_07
Patent number
US09394309B2

Reaction notes

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