2-Bromo-4-nitrotoluene → HCID 89700065, compound

HRID 1055685Notes

Reaction equation

HRID 1055685 reaction equation
[CH2:1]([O:3][CH:4]([O:18][CH2:19][CH3:20])[CH2:5][N:6]1[C:10]([NH2:11])=[CH:9][C:8]([C:12]2[CH:17]=[N:16][CH:15]=[CH:14][N:13]=2)=[N:7]1)[CH3:2].Br[C:22]1[CH:27]=[C:26]([N+:28]([O-:30])=[O:29])[CH:25]=[CH:24][C:23]=1[CH3:31]>>[CH2:19]([O:18][CH:4]([O:3][CH2:1][CH3:2])[CH2:5][N:6]1[C:10]([NH:11][C:22]2[CH:27]=[C:26]([N+:28]([O-:30])=[O:29])[CH:25]=[CH:24][C:23]=2[CH3:31])=[CH:9][C:8]([C:12]2[CH:17]=[N:16][CH:15]=[CH:14][N:13]=2)=[N:7]1)[CH3:20]

Participants

3

Reactant 2

HCID 821892-Bromo-4-nitrotolueneHCID 89700268HCID 89700268, compound

Product 1

HCID 89700065HCID 89700065, compound

Procedure

Analogously to Example 13A/Step 1, 1.16 g (4.18 mmol) of the compound of Example 59A and 994 mg (4.60 mmol) of 2-Bromo-4-nitrotoluene gave 1.64 g (86% of theory) of the title compound.

Sources & evidence

ORD record
ord-085d02c34a464f1996956515431bacc3
Source dataset
uspto-grants-2016_07
Patent number
US09394309B2

Reaction notes

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